FMC and IMS

IMS-IMS and IMS-IMS-IMS/MS for separating peptide and protein fragment ions.

Multidimensional ion mobility spectrometry (IMS-IMS and IMS-IMS-IMS) techniques have been combined with mass spectrometry (MS) and investigated as a means of generating and separating peptide and protein fragment ions. When fragments are generated inside a drift tube and then dispersed by IMS prior to MS analysis, it is possible to observe many features that are not apparent from MS analysis al...

Quantitative modeling and analysis with FMC-QE

The modeling and evaluation calculus FMC-QE, the Fundamental Modeling Concepts for Quantitative Evaluation [143], extends the Fundamental Modeling Concepts (FMC) for performance modeling and prediction. In this new methodology, the hierarchical service requests are in the main focus, because they are the origin of every service provisioning process. Similar to physics, these service requests ar...

IMS Application Developer's Handbook - creating and Deploying Innovative IMS Applications

An IMS-IMS analogue of MS-MS.

The development of a new ion mobility/mass spectrometry instrument that incorporates a multifield drift tube/ion funnel design is described. In this instrument, individual components from a mixture of ions can be resolved and selected on the basis of mobility differences prior to collisional activation inside the drift tube. The fragment ions that are produced can be dispersed again in a second...

FMC: An Approach for Privacy Preserving OLAP

To preserve private information while providing thorough analysis is one of the significant issues in OLAP systems. One of the challenges in it is to prevent inferring the sensitive value through the more aggregated non-sensitive data. This paper presents a novel algorithm FMC to eliminate the inference problem by hiding additional data besides the sensitive information itself, and proves that ...